Ini kerana jika Intensive
Care Unit Hospital tempat yang tersayang anda itu ada bakteria CRE, dan saudara
anda dijangkiti oleh kuman ini, maka peluang untuk saudara yang tersayang anda mati
awal mungkin tinggi kerana bakteria ini sukar dirawat akibat rintangan
kekebalan terhadap antibiotik yang sangat tinggi.
Rintangan antibiotik yang
sangat tinggi ini adalah disebabkan oleh perangai kebanyakan pengamal perubatan
sendiri yang suka memberikan antibiotik secara berleluasa walaupun pesakit
tidak memerlukan antibiotik di peringkat klinik !!!
30:41
Telah lahirlah bencana di darat dan di laut, kerana usaha tangan manusia,
supaya Allah merasakan kepada mereka sebahagian dari (balasan) perbuatan yang
mereka perbuat, mudah mudahan mereka kembali (taubat).
42:30
Apa apa musibah (melapetaka) yang menimpa kamu , maka disebabkan usaha tanganmu
sendiri dan dimaafkan Allah kebanyakkannya.
Carbapenem-resistant Enterobacteriaceae (CRE) Infection: Patient FAQs
What are CRE?
CRE, which stands for
Carbapenem-resistant Enterobacteriaceae, are a family of germs that are
difficult to treat because they have high levels of resistance to antibiotics.
CRE are an important emerging threat to public health.
Common Enterobacteriaceae include Klebsiella species and Escherichia coli (E. coli). These
germs are found in normal human intestines (gut). Sometimes these bacteria can
spread outside the gut and cause serious infections, such as urinary tract
infections, bloodstream infections, wound infections, and pneumonia.
Enterobacteriaceae can cause infections in people in both healthcare and
community settings.
Carbapenems are a group of antibiotics that are usually reserved
to treat serious infections, particularly when these infections are caused by
germs that are highly resistant to antibiotics. Sometimes carbapenems are
considered antibiotics of last resort for some infections. Some
Enterobacteriaceae can no longer be treated with carbapenems because they have
developed resistance to these antibiotics (i.e., CRE); resistance makes the
antibiotics ineffective in killing the resistant germ. Resistance to
carbapenems can be due to a few different mechanisms. One of the more common
ways that Enterobacteriaceae become resistant to carbapenems is due to
production of Klebsiella
pneumoniaecarbapenemase (KPC). KPC is an enzyme that is produced by
some CRE that was first identified in the United States around 2001. KPC breaks
down carbapenems making them ineffective. Other enzymes, in addition to
KPC, can breakdown carbapenems and lead to the development of CRE, but they are
uncommon in the United States.
How are CRE spread?
To get a CRE infection, a person must be exposed to CRE germs. CRE
germs are usually spread person to person through contact with infected or
colonized people, particularly contact with wounds or stool. CRE can cause
infections when they enter the body, often through medical devices like ventilators,
intravenous catheters, urinary catheters, or wounds caused by injury or
surgery.
Who is most likely to get an infection
with CRE?
Healthy people usually don’t get CRE infections. CRE primarily
affect patients in acute and long-term healthcare settings, who are being
treated for another condition. CRE are more likely to affect those patients who
have compromised immune systems or have invasive devices like tubes going into
their body. Use of certain types of antibiotics might also make it more likely for
patients to get CRE. CRE have been spread during ERCP (endoscopic retrograde
cholangiopancreatography), a medical procedure that involves inserting a
specialized endoscope commonly called a duodenoscope into the mouth and down to
the intestine where the bile duct attaches.
Can CRE be treated?
Many people with CRE will have the germ in or on their body
without it producing an infection. These people are said to be colonized with
CRE, and they do not need antibiotics for the CRE. If the CRE are causing an
infection, the antibiotics that will work against it are limited but some
options are often available. In addition, some infections might be able to be
treated with other therapies, like draining the infection. Strains that have
been resistant to all antibiotics are very rare but have been reported.
What are some things hospitals are
doing to prevent CRE infections?
To prevent the spread of CRE, healthcare personnel and facilities
can follow infection-control precautions provided by CDC. These include:
·
Washing hands with soap and water or an alcohol-based hand
sanitizer before and after caring for a patient
·
Carefully cleaning and disinfecting rooms and medical equipment
·
Wearing gloves and a gown before entering the room of a CRE
patient
·
Keeping patients with CRE infections in a single room or sharing a
room with someone else who has a CRE infection
·
Whenever possible, dedicating equipment and staff to CRE patients
·
Removing gloves and gown and washing hands before leaving the room
of a CRE patient
·
Only prescribing antibiotics when necessary
·
Removing temporary medical devices as soon as possible
·
Sometimes, hospitals will test patients for these bacteria to
identify them early to help prevent them from being passed on to other patients
What can patients do to prevent CRE
infections?
Patients should:
·
Tell your doctor if you have been hospitalized in another facility
or country.
·
Take antibiotics only as prescribed.
·
Expect all doctors, nurses, and other healthcare providers wash
their hands with soap and water or an alcohol-based hand rub before and after
touching your body or tubes going into your body. If they do not, ask
them to do so.
·
Clean your own hands often, especially:
o Before
preparing or eating food
o Before
and after changing wound dressings or bandages
o After
using the bathroom
o After
blowing your nose, coughing, or sneezing
·
Ask questions. Understand what is being done to you, the risks and
benefits.
What if I have CRE?
Follow your healthcare provider’s instructions. If your provider
prescribes you antibiotics, take them exactly as instructed and finish the full
course, even if you feel better. Wash your hands, especially after you have
contact with the infected area and after using the bathroom. Follow any other
hygiene advice your provider gives you.
I am caring for someone with CRE
at home; do I need to take special precautions?
CRE have primarily been a problem among people with underlying
medical problems, especially those with medical devices like urinary catheters
or those with chronic wounds. Otherwise healthy people are probably at
relatively low risk for problems with CRE. People providing care at home for
patients with CRE should be careful about washing their hands, especially after
contact with wounds or helping the CRE patient to use the bathroom or after
cleaning up stool. Caregivers should also make sure to wash their hands before
and after handling the patient’s medical device (e.g., urinary catheters). This
is particularly important if the caregiver is caring for more than one ill
person at home. In addition, gloves should be used when anticipating contact
with body fluids or blood.
Is CRE infection related to
medical care abroad?
A variety of enzymes produced by Enterobacteriaceae make them
resistant to carbapenems. Several of these enzymes appear to be more
common in other countries than they are in the United States. As with medical
care in the United States, medical care abroad can be associated with healthcare–associated
infections and/or resistant bacteria. Learn about those risks and how to minimize them.
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